Qinwen Wang Selected Research

Cognitive Dysfunction

1/2023	Associations of serum DNA methylation levels of chemokine signaling pathway genes with mild cognitive impairment (MCI) and Alzheimer's disease (AD).
4/2020	CSB6B prevents β-amyloid-associated neuroinflammation and cognitive impairments via inhibiting NF-κB and NLRP3 in microglia cells.
3/2020	Pharmacological Mechanisms Underlying the Neuroprotective Effects of Alpinia oxyphylla Miq. on Alzheimer's Disease.
2/2020	Inhibition of acetylcholinesterase activity and β-amyloid oligomer formation by 6-bromotryptamine A, a multi-target anti-Alzheimer's molecule.
1/2020	Calcium-Sensing Receptor Mediates β-Amyloid-Induced Synaptic Formation Impairment and Cognitive Deficits via Regulation of Cytosolic Phospholipase A2/Prostaglandin E2 Metabolic Pathway.
7/2019	Significant association of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) rs3846662 and sirtuin 1 (SIRT1) rs7895833 and apolipoprotein E (APOE) hypermethylation with mild cognitive impairment (MCI).
1/2019	p-Hydroxybenzyl Alcohol Prevents Memory Deficits by Increasing Neurotrophic Factors and Decreasing Inflammatory Factors in a Mice Model of Alzheimer's Disease.
1/2018	Taxifolin prevents β-amyloid-induced impairments of synaptic formation and deficits of memory via the inhibition of cytosolic phospholipase A2/prostaglandin E2 content.
1/2018	Tacrine(10)-hupyridone, a dual-binding acetylcholinesterase inhibitor, potently attenuates scopolamine-induced impairments of cognition in mice.
5/2017	Fucoxanthin Inhibits β-Amyloid Assembly and Attenuates β-Amyloid Oligomer-Induced Cognitive Impairments.

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Qinwen Wang Research Topics

Disease

31	Alzheimer Disease (Alzheimer's Disease) 01/2023 - 11/2004
18	Cognitive Dysfunction 01/2023 - 04/2011
7	Memory Disorders (Memory Loss) 01/2021 - 08/2013
6	Neuroinflammatory Diseases 11/2023 - 08/2013
6	Neoplasms (Cancer) 01/2017 - 04/2013
5	Inflammation (Inflammations) 01/2022 - 03/2008
4	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2023 - 06/2010
3	Reperfusion Injury 04/2024 - 01/2023
3	Pain (Aches) 04/2020 - 12/2015
3	Substance-Related Disorders (Drug Abuse) 09/2018 - 06/2016
3	Amyloid Plaque 01/2018 - 03/2008
3	Prostatic Neoplasms (Prostate Cancer) 04/2013 - 03/2011
2	Myocardial Ischemia (Ischemic Heart Diseases) 04/2024 - 01/2023
2	Chronic Pain 01/2019 - 12/2015
2	Leukemia 05/2017 - 09/2014
2	Obesity 03/2016 - 03/2014
1	Ischemia 04/2024
1	Ethylmalonic encephalopathy 04/2024
1	Hypertension (High Blood Pressure) 01/2024
1	Ischemic Stroke 01/2024
1	Stroke (Strokes) 01/2024
1	Dysbiosis 12/2023
1	Postoperative Cognitive Complications 12/2023
1	Hypoxia (Hypoxemia) 11/2023
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2022
1	Lung Injury 01/2022
1	Constipation 01/2022
1	Wounds and Injuries (Trauma) 04/2019
1	Hypersensitivity (Allergy) 01/2018

Drug/Important Bio-Agent (IBA)

18	Amyloid (Amyloid Fibrils)IBA 01/2023 - 11/2004
8	Proteins (Proteins, Gene)FDA Link 04/2024 - 11/2004
7	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2017 - 01/2014
4	RNA (Ribonucleic Acid)IBA 04/2024 - 01/2020
4	CytokinesIBA 01/2024 - 03/2008
4	Scopolamine (Hyoscine)FDA Link 02/2020 - 01/2016
4	Peptides (Polypeptides)IBA 01/2020 - 11/2011
4	Amyloid beta-PeptidesIBA 08/2014 - 03/2008
3	CurcuminIBA 04/2024 - 01/2017
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2014 - 09/2011
2	Messenger RNA (mRNA)IBA 04/2024 - 12/2015
2	6-methyladenineIBA 04/2024 - 01/2023
2	Neuroprotective AgentsIBA 03/2020 - 01/2017
2	LipopolysaccharidesIBA 04/2019 - 01/2017
2	IntegrinsIBA 04/2019 - 10/2008
2	Fast Green FCFIBA 01/2019 - 01/2018
2	Opioid Receptors (Opioid Receptor)IBA 11/2018 - 09/2018
2	NeurotoxinsIBA 01/2018 - 10/2017
2	Donepezil (Aricept)FDA LinkGeneric 01/2018 - 01/2016
2	Dinoprostone (PGE2)FDA Link 01/2018 - 03/2008
2	fucoxanthinIBA 05/2017 - 03/2016
2	indirubinIBA 05/2017 - 01/2017
2	AntioxidantsIBA 01/2017 - 03/2016
2	bis(propyl)cognitinIBA 01/2016 - 06/2010
2	bis(heptyl)cognitinIBA 07/2015 - 06/2010
2	Rosiglitazone (Avandia)FDA Link 08/2014 - 01/2014
2	Memantine (Namenda)FDA Link 04/2011 - 06/2010
1	Thiosulfate Sulfurtransferase (Rhodanese)IBA 04/2024
1	LyasesIBA 04/2024
1	Oxygen (Dioxygen)IBA 04/2024
1	CystathionineIBA 04/2024
1	Indicators and Reagents (Reagents)IBA 01/2024
1	Interleukin-6 (Interleukin 6)IBA 01/2024
1	Interleukin-4 (Interleukin 4)IBA 01/2024
1	Interleukin-10 (Interleukin 10)IBA 01/2024
1	LipidsIBA 01/2024
1	Interleukin-2 (IL2)IBA 01/2024
1	N- (2(R)- 2- (hydroxamidocarbonylmethyl)- 4- methylpentanoyl)- L- tryptophan methylamideIBA 11/2023
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 11/2023
1	Molecular Chaperones (Chaperone, Molecular)IBA 08/2023
1	Hormones (Hormone)IBA 08/2023
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 08/2023
1	ChemokinesIBA 01/2023
1	DiarylheptanoidsIBA 01/2023
1	Arachidonic Acid (Vitamin F)IBA 01/2022
1	Air Pollutants (Pollutants, Air)IBA 01/2022
1	aluminum sulfate (alum)IBA 01/2022
1	pontamine sky blueIBA 04/2020
1	Analgesics (Analgesic Drugs)IBA 04/2020
1	oxyphylla AIBA 03/2020
1	5-hydroxymethylcytosineIBA 01/2020
1	evodiamineIBA 01/2020
1	BerberineIBA 01/2020
1	Apolipoproteins E (ApoE)IBA 07/2019
1	3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)IBA 07/2019
1	ApolipoproteinsIBA 07/2019
1	Oxidoreductases (Dehydrogenase)IBA 07/2019
1	Sirtuin 1IBA 07/2019
1	extracellular matrix receptorIBA 04/2019
1	4-hydroxybenzyl alcoholIBA 01/2019
1	Nerve Growth Factors (Neurotrophins)IBA 01/2019
1	Dopamine Receptors (Dopamine Receptor)IBA 02/2018
1	taxifolinIBA 01/2018
1	Coloring Agents (Dyes)IBA 01/2018
1	AlginatesIBA 01/2018
1	Freund's AdjuvantIBA 01/2018
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 05/2017

Therapy/Procedure

3	Therapeutics 05/2017 - 05/2002
2	Chinese Traditional Medicine (Traditional Chinese Medicine) 03/2020 - 01/2020
1	Electroacupuncture 12/2023
1	Aftercare (After-Treatment) 01/2022